Having lost both the singles on the opening day, the Yuki-Saketh pair did put up a fight before losing to the fancied Norwegian duo in an hour and 50 minutes.
The 85-ranked Indian lost his first round match 6-2, 3-6, 3-6, 2-6 in two hour and 38 minutes.
The 44-year-old Bopanna had also lost in the men's doubles in the third round when he and his Australian partner Matthew Ebden were beaten by the Argentine duo of Maximo Gonzalez and Andres Molteni.
An unresponsive treatment and the monotony of the long rehabilitation almost convinced Yuki Bhambri to hang his racquet for good but a voice within kept telling him that he could still pursue the game he is so passionate about.
The win was a first for Ferrari in Mexico since 1990 and fourth of Carlos Sainz's career.
Yuki Bhambri crushed Argentina's Renzo Olivo in straight sets to move into the final round of the ATP Miami Masters qualifiers but Ramkumar Ramanathan was ousted in the opening round.
Sumit Nagal crashed out of the US Open after suffering a straight-set defeat against Dutch player Tallon Griekspoor in the first round. The 27-year-old Indian tennis ace, competing in his fourth Grand Slam this year, was beaten 1-6, 3-6, 6-7(6-8) late in the day at Flushing Meadows, New York.
Davis Cupper N Sriram Balaji and Yuki Bhambri entered the men's doubles second round at the US Open with their respective partners in New York on Wednesday.
Max Verstappen, who could seal his fourth successive championship on Saturday, will line up fifth on the starting grid
Yuki Bhambri geared up for India's Davis Cup tie against Czech Republic by annexing his first Challenger level singles title of the season as he defeated local favourite Di Wu in the final of the $50,000 tournament, in Shanghai on Sunday.
Yuki Bhambri and his Dutch partner Robin Hasse went down in straight sets to Ivan Dodig and Austin Krajicek at the Dubai Duty Free Tennis Championships.
India has never beaten Sweden in five attempts in the Davis Cup.
However, Ramkumar Ramanathan and Ankita Raina's campaign ended in the first round itself.
Yuki Bhambri made his first doubles semi-finals of the ATP 500 tour.
In doubles, probably for first time, six players are featuring in the men's draw.
Another Indian pair of N Sriram Balaji and Vishnu Vardhan will also be seen in the semi-finals after their opponents, Gianluca Mager and Emil Ruusuvuori withdrew from the last-eight match due to an injury to the former.
Yuki Bhambri is in line to win his second Challenger level singles title of the season as he advanced to the summit clash after his opponent withdrew due to a lower back problem in Shanghai.
Red Bull's Max Verstappen dealt Lando Norris a shattering blow in their Formula One title battle by winning a wet and chaotic Sao Paulo Grand Prix from 17th on the grid.
Yuki Bhambri went down fighting while Ramkumar Ramanathan suffered a tame defeat as the two Indians bowed out of the French Open Qualifiers, in Paris, on Monday.
Yuki Bhambri broke back into the top-200 after 15 months, thanks to a solid performance at the ATP Taipei Challenger, where he made the semi-finals to leap to number 186 in the latest rankings.
Rohan Bopanna will pair with N Sriram Balaji in the men's doubles event at the Paris Olympics.
The final phase of qualifying was halted, with only Piastri and Haas' Nico Hulkenberg having set times, when Sainz slammed backwards into the barriers at the final corner as he prepared to start his flying lap.
This is Balaji's maiden French Open match victory and overall his fourth in Grand Slams.
Clay is not his preferred surface but Yuki Bhambri says he is ready for the French Open challenge and staying patient during long rallies will be key for his maiden campaign at the Roland Garros.
Bidding for his second Grand Slam title of the year, India's Yuki Bhambri stormed into the boys' singles quarter-finals of the junior US Open in New York on Thursday. Yuki edged past local lad Jack Sock 6-4, 6-3 in the third round.
India's top singles player Yuki Bhambri on Sunday withdrew from the Chennai Open as he is yet to recover from his elbow injury.
Yuki Bhambri's maiden appearance at the French Open ended with a first round defeat as he lost his opening men's singles match to Belgium's Ruben Bemelmans in straight sets, in Paris, on Tuesday.
Yuki Bhambri, who failed to rise to the occasion and suffered a straight-set bashing at the hands of Dusan Lajovic in the opening singles, today said unforced errors and failure to push the opponent hard had done in him in the Davis Cup World Group Playoff tie in Bangalore.
Yuki Bhambri saved a match point in a gruelling battle against Peter Polansky before securing a place in the second round of the Aegon Challenger event, in Ilkley.
Yuki Bhambri, making a comeback from an elbow injury, on Sunday qualified for the singles main draw of the Chennai Open.
Another Indian, Yuki Bhambri and his Dutch partner Robin Haase also progressed to the quarter-finals.
India's Yuki Bhambri and his French partner Albano Olivetti crashed out of Marrakech Open after losing the hard-fought semifinal to second seeds Lucas Miedler and Alexander Erler of Austria.
There will be no Indian presence in the singles main draw at the Australia Open this year with Yuki Bhambri stumbling at the final hurdle, losing his third and final qualifying round match to Ernesto Escobedo, in Melbourne on Saturday.
Yuki Bhambri shocked third seed Dmitry Tursunov to progress to the second round of the ATP Challenger, but his doubles partner, Divij Sharan, went down fighting to sixth seed Yuichi Sugita, in Seoul, on Tuesday. Yuki scored a 6-4, 7-6(5) victory over his formidable Russian opponent, once a top-20 player, in the first round of the US $100,000 hard court event.
Since Yuki Bhambri, ranked 94, is likely to make the cut for the US Open, the AITA selection committee exempted him.
Yuki Bhambri continued his rich vein of form as he swept aside Mirza Basic of Bosnia-Herzegovina in straight sets to storm into the second round of the Miami Open.
Yuki Bhambri recovered well from a poor start to beat New Zealand's Michael Venus in a three-setter and advance to the singles quarter-finals of the ATP Challenger event in Traralgon, Australia.
Balaji also showed that he can quickly adapt to conditions when he was asked to do the singles duty during the Davis Cup tie against Pakistan on grass. The rival was not of the highest quality but Balaji showed that he was willing to come out of his comfort zone if the team demands.
India's Yuki Bhambri and his Dutch partner Robin Haase squandered three match points in the deciding set to go down against Nicolas Barrientos of Colombia and Rafael Matos of Brazil in the Australian Open men's doubles first round in Melbourne on Tuesday.
Jehan Daruvala's racing career may not have taken the path he envisioned, but the Indian driver isn't dwelling on missed opportunities.
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